WebSep 22, 2011 · With the use of fine mapping of the PEAR1 locus and sequencing of the PEAR1 gene, we have now identified a common variant (rs12041331, genetic location chromosome 1: 155136338, NCBI build 36.3) in intron 1 of PEAR1 that accounts most strongly for the association signal between the PEAR1 locus and platelet function … WebWelcome to PEAR Portal! If your provider organization is not yet enrolled, select Register My Organization below. Only participating providers in an Independence Blue Cross, …
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WebJul 8, 2015 · PEAR1 expression in human ECs. (A) Immunohistochemical staining for PEAR1 and CD31, illustrating PEAR1-protein expression in ECs of human liver, lung, and kidney, as indicated (×100 left panel, ×1000 middle panel, and ×100 right panel).(B) IF staining (×630) for CD31 (red), PEAR1 (green), and merge (white colour represents the calculated overlap) … WebJun 27, 2013 · Platelet endothelial aggregation receptor-1 (PEAR1) participates in platelet aggregation via sustaining αIIbβ3 activation. To investigate the role of PEAR1 in platelet formation, we monitored and manipulated PEAR1 expression in vitro in differentiating human CD34 + hematopoietic stem cells and in vivo in zebrafish embryos. PEAR1 … compression socks that stay up
Variation of PEAR1 DNA methylation influences platelet and …
WebPEAR1 regulates expansion of activated broblasts and deposition of extracellular matrix in pulmonary brosis Yan Geng 1,8,LinLi1,8,JieYan1,KevinLiu2,AizhenYang3, ... (IPF) 3,4.IPFhas WebJan 31, 2024 · The culture supernatants of LFs from IPF patients, as compared to controls, showed an increase in plasmin activity after plasminogen incubation (5–15 μg/mL), corresponding with increased levels ... WebMay 22, 2024 · PEAR1 is a type of receptor tyrosine kinase (RTK) causing platelet- platelet adhesion via the EMI domain (EMILIN Family Domain) in its extracellular part and … echo light bulbs for alexa