Bioplex interactome
WebJul 16, 2015 · The resulting network (BioPlex) contains 23,744 interactions among 7,668 proteins with 86% previously undocumented. BioPlex accurately depicts known complexes, attaining 80%–100% coverage for … WebBioPlex ( b iophysical i nteractions of O RFeome -based com plex es) is an open access resource for studying protein -protein interactions. [1] [2] [3] It is the result of …
Bioplex interactome
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WebNX_O76039 - CDKL5 - Cyclin-dependent kinase-like 5 - Interactions. Mediates phosphorylation of MECP2 (PubMed:15917271, PubMed:16935860). May regulate ciliogenesis (PubMed:29420245). WebJan 1, 2024 · NX_P11926 - ODC1 - Ornithine decarboxylase - Function. Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA …
WebWe have a number of very exciting projects including quantitative proteomic analysis of the CCLE, the BioPlex Interactome, intelligent data acquisition strategies, and many more... Team Gygi. Working Together, everywhere. See the Team! Explore Recent Work. WebBioPlex Explorer. To enable search and download of the BioPlex Interactome datasets, we developed the web application - BioPlex Explorer. With the Explorer, users can search for their favorite protein within the BioPlex interactome and investigate subnetworks, network communities, or cell-line specific interactions. Explore!
WebMay 27, 2024 · Nevertheless, BioPlex incompletely models the interactome because (1) only a fraction of human proteins has been profiled, and (2) although the interactome is dynamic, we have only profiled interactions in a single context. Download : Download high-res image (2MB) Download : Download full-size image; Figure 1. WebBioPlex 3.0, Part 1 (Unpublished) Protein interactions in the BioPlex network following reanalysis of all data from BioPlex 2.0 plus an additional ~1500 unpublished AP-MS experiments. This is the first of two releases that together include all IP's in BioPlex 3.0.
WebJan 5, 2024 · BioPlex is a large-scale interactome data set based on AP-MS of baits from the human ORFeome. The latest BioPlex data set release (BioPlex 2.0) contains 56 553 interactions from 5891 AP-MS experiments. To improve community access to this vast compendium of interactions, we developed BioPlex Display, which integrates individual …
WebA mode is the means of communicating, i.e. the medium through which communication is processed. There are three modes of communication: Interpretive Communication, … lists and arrays pythonWebJul 16, 2015 · Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network … lists and filters activity simulator taskWebWe built a new, real-time database search (RTS) platform, Orbiter, to combat the SPS-MS3 method’s longer duty cycles. RTS with Orbiter eliminates SPS-MS3 scans if no peptide matches to a given spectrum. With Orbiter’s online proteomic analytical pipeline, which includes RTS and false discovery rate analysis, it was possible to process a ... lists and tablesWebBioGRID Interaction 3112433 Between TNFRSF13B And C1QBP. Toggle navigation. Bio GRID 4.4 impact displays incWebNov 23, 2024 · A comparison with the BioPlex interactome revealed an overlap of 9 proteins, yet only 40 are listed, hence 29% of the proteins were identified as common to our dataset (Supplementary fig. S8B). impact dissolvehttp://gpmdb.thegpm.org/protein/accession/ENSP00000222005 impact displaysimpact distribution