Adiponectin-cre是什么

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August undefined, 2024

WebAdipoq-Cre BAC transgenic mice are a Cre-lox tool for deletion of floxed sequences in white adipose tissue and brown adipose tissue, but not in activated or resident macrophages. … WebJul 15, 2024 · 创新点：该研究利用Adiponectin-Cre驱动Pwwp2b脂肪组织特异性敲除鼠模型及棕色脂肪细胞系等，揭示了PWWP2B在棕色/米色脂肪组织中通过招募并稳定组蛋白 …

Adiponectin, Leptin, and Fatty Acids in the Maintenance of …

WebMA1-054 detects adiponectin from human, rabbit and mouse samples. MA1-054 has been used successfully in Western blot, immunofluorescence, and ELISA procedures. By Western blot this antibody detects ~30 kDa protein representing Adiponectin in 3T3-L1 adipocytes. Immunofluorescence and ELISA of Adiponectin can also be performed using MA1-054. WebThe promoter for adiponectin, a hormone secreted by mature adipocytes, has been used by multiple groups to generate adipocyte-specific Cre lines. 20, 21 The most widely used Adiponectin-Cre R line 12 has been shown several times to be specific to adipocytes, 9, 16, 18 and useful for targeting mature adipocytes in vivo. bodies of water that surround mexico

复旦大学潘东宁团队AS：PWWP2B蛋白在调控脂肪组织产热功能 …

http://www.xml-data.org/XMSYXB/html/2024/12/20241203.htm WebJun 18, 2024 · Adiponectin is one such factor, secreted in large quantities primarily from adipose tissue. Adiponectin is posttranslationally modified from a 30-kDa monomeric protein into different multimers (low molecular weight or trimer, middle molecular weight or hexamer, and high molecular weight) and secreted into the circulation. WebAdiponectin, a 30 kDa protein, is the most abundant serum adipokine, secreted exclusively by the adipose tissue. Adiponectin, in contrast to leptin, is down-regulated in obesity … clock work replacement with pendulem

Adipoq-Cre小鼠--兰博模型LABMODEL 兰博动物LABANIMAL 兰 …

Addgene: Cre-lox system

WebThe Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. Using … WebThe Cre-lox system, derived from P1 bacteriophage, is a potent and specific system for controlling gene expression. The protein Cre recombinase recognizes 34 bp loxP sites, and the orientation and location of the loxP sites determines how the genetic material will be rearranged. The schematic below shows the three types of rearrangements ... bodies of work fotoausstellungWebJun 24, 2024 · Cre- littermates serve as control. In keeping with the unique expression of adiponectin Cre in adipocytes and their precursors all Cre+ products of the mating contain no discernable WAT confirmed by virtually undetectable circulating adiponectin or leptin as well as visfatin and, resistin . BAT is also absent and as a result, FF mice are cold ... bodies of water warmed by a magmatic system

"WebApr 4, 2024 · To determine the metabolic effects of direct FGF21 signaling to adipose tissue, we generated mice lacking the obligate FGF21 coreceptor, β-klotho (gene symbol: Klb), specifically in adipose tissue (KLB AdipoKO mice) by crossing KLB fl/fl mice with Adiponectin-Cre transgenic mice. As expected, β-klotho mRNA (Figure 1A ) and protein … " - Adiponectin-cre是什么

Adiponectin-cre是什么

WebFeb 14, 2013 · To circumvent the possible side effects of gene deletion of the aP2-Cre in tissues other than adipocytes, two laboratories have developed adiponectin-Cre transgenic mice (Adipoq-Cre), with expression of a Cre recombinase driven by the promoter/regulatory regions of the mouse adiponectin locus using a bacterial artificial chromosome (BAC ... Web脂肪细胞因子adiponectin的研究进展脂肪,研究,因子,研究进展,细胞因子,脂肪细胞,前脂肪细胞

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WebFeb 10, 2024 · ABSTRACT. The Adipoq-Cre transgenic mouse is widely used in the development of adipocyte-specific genetic manipulations for the study of obesity and type 2 diabetes. In the process of developing a new mouse model utilizing the adipocyte selective Adipoq-Cre transgenic mouse, strong genetic linkage between a gene of interest, … WebThe Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. ... Characterization of the adiponectin promoter + Cre recombinase insertion in the Tg(Adipoq-cre)1Evdr mouse by targeted locus amplification and droplet digital PCR …

WebSep 29, 2024 · Discover how adiponectin levels and adiponectin function influence body weight and health, and whether you need adiponectin testing. Adiponectin is a molecule secreted mainly by the body’s fat cells ( adipocytes) that is linked to weight loss and weight gain. In this article, discover adiponectin hormone functions, the adiponectin-obesity ... WebMay 5, 2016 · While previous studies show that the β-cell expresses leptin receptors (Seufert et al., 1999), Soedling and colleagues recently reported that leptin receptor mRNA expression in isolated β-cells was at or below the level of detection and, using a newly developed Cre to specifically target Leptin receptor deletion to the β-cell, the authors ...

http://www.labmodel.cn/mod_product-view-p_id-4096.html WebAdipoq-Cre BAC transgenic mice are a Cre-lox tool for deletion of floxed sequences in white adipose tissue and brown adipose tissue, but not in activated or resident macrophages. …

WebAdiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels as well as fatty acid …

http://www.ichacha.net/adiponectin.html clockwork restaurant \\u0026 barWeb该Cre小鼠与FloxP小鼠交配后，在Cre特异表达的组织或者器官或细胞中，两个FloxP位点间的外显子或元件将被删除，达到条件性敲除或过表达的目的。 Cre-loxP重组系统是一种位点特异的基因重组技术，被广泛应用于特异位点的基因敲除、基因插入、基因翻转和基因 ... bodies of work crossword clockwork restaurantWebMar 21, 2024 · ADIPOQ (Adiponectin, C1Q And Collagen Domain Containing) is a Protein Coding gene. Diseases associated with ADIPOQ include Adiponectin, Serum Level Of, Quantitative Trait Locus 1 and Fatty Liver Disease.Among its related pathways are AMP-activated protein kinase signaling and Integration of energy metabolism.Gene Ontology … clockwork retail ltdWebThe adiponectin gene is located on chromosome 3q27. This gene encodes a 244-amino acid protein composed of an amino-terminal signal peptide, a collagen-like domain at the N-terminus, and a globular domain at the C-terminus (Fig. 1).The globular domain is homologous to proteins such as collagens VIII and X and complement factor C1q 25 and … bodies of water worksheet 6th gradeWeb中文翻译手机版. 人脂联素. "mouse adiponectin"中文翻译小鼠脂联素. "rabbit adiponectin"中文翻译兔脂联素. "rat adiponectin"中文翻译大鼠脂联素. "adiponitrile"中文翻译己二腈; … bodies old corner the wireWebDec 3, 2024 · 脂联素（adiponectin，AdipoQ）是一种主要由脂肪组织分泌的脂肪细胞因子。近年来的研究表明，脂联素在调节动物脂质代谢中发挥重要的作用。 clockwork retail